CNS Spectr. 2010;15:7(Suppl 8):16
Funding for this activity has been provided by an educational grant from Lilly USA, LLC.
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Mount Sinai School of Medicine and MBL Communications, Inc. The Mount Sinai School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.
The Mount Sinai School of Medicine designates this educational activity for a maximum of 2 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Faculty Disclosure Policy Statement
It is the policy of the Mount Sinai School of Medicine to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME-sponsored educational activities. All faculty participating in the planning or implementation of a sponsored activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. Presenters must also make a meaningful disclosure to the audience of their discussions of unlabeled or unapproved drugs or devices. This information will be available as part of the course material.
Statement of Need and Purpose
Although considerable progress has been made in schizophrenia management, challenges remain. The treatment of schizophrenia is complicated by medical and psychiatric comorbidities and different treatment stages, resulting in frequent polypharmacy and potential side effect/adverse event risks including significant weight gain. Schizophrenia is associated with increased medical comorbidity likely caused by interactions between lifestyle, environment, and the disease itself. The Clinical Antipsychotic Trials of Intervention Effectiveness data indicated that a large number of schizophrenia patients met metabolic syndrome criteria at baseline and that few were receiving treatment for metabolic-related conditions: rates of nontreatment were 30.2% for diabetes, 62.4% for hypertension, and 88% for dyslipidemia.
At the completion of this activity, participants should be better able to:
• Identify the long-term health impact of common psychiatric and medical comorbidities in patients with schizophrenia
• Assess current evidence on the efficacy, safety, and tolerability of treatments for schizophrenia that address comorbid psychiatric and medical conditions to create targeted care plans
• Integrate psychoeducation, establish a clinician-patient alliance to provide a supportive care environment, and address real world clinical concerns
This activity is designed to meet the educational needs of psychiatrists.
Faculty Affiliations and Disclosures
Leslie Citrome, MD, MPH, is professor in the Department of Psychiatry at New York University School of Medicine in New York City, and director of the Clinical Research and Evaluation Facility at the Nathan S. Kline Institute for Psychiatric Research in Orangeburg, New York. Dr. Citrome has received research support from AstraZeneca, Eli Lilly, Janssen, and Pfizer; is a consultant and advisor to Azur, Eli Lilly, GlaxoSmithKline, Janssen, Merck, Novartis, and Pfizer; has received compensation for services on the advisory boards of Eli Lilly, Janssen, Merck, Novartis, and Pfizer; has received honoraria for lectures, papers, and teaching from AstraZeneca, Azur, Eli Lilly, Merck, Novartis, and Pfizer; has received consulting fees from Azur, GlaxoSmithKline, and Janssen; and owns stock in Bristol-Myers Squibb, Eli Lilly, Johnson & Johnson, Merck, and Pfizer.
Oliver Freudenreich, MD, is assistant professor of psychiatry at Harvard Medical School in Cambridge, Massachusetts, and director of the First Episode and Early Psychosis program at Massachusetts General Hospital in Boston. Dr. Freudenreich has received research support from Pfizer, honoraria from Reed Medical Education, and consulting fees from Beacon Health Strategies.
Peter J. Weiden, MD, is professor of psychiatry and director of the Psychotic Disorders program at the University of Illinois in Chicago. Dr. P.J. Weiden is a consultant to AstraZeneca, Bristol-Myers Squibb/Otsuka, Eli Lilly, Forest, Merck, Novartis, Ortho-McNeil-Janssen, Pfizer, Takeda, Vanda, and Wyeth; has received grant support from the National Institute of Mental Health and Ortho-McNeil-Janssen; and is a speaker for Novartis, Ortho-McNeil-Janssen, and Pfizer.
Michael Weiden, MD, is associate professor of pulmonary and critical care medicine at the New York University School of Medicine in New York. Dr. M. Weiden reports no affiliation with or financial interest in any organization that may pose a conflict of interest.
CME Course Director James C.-Y. Chou, MD, is associate professor of psychiatry at Mount Sinai School of Medicine in New York City. Dr. Chou has received honoraria from AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen, Merck, Novartis, and Pfizer.
Margaret McNamara McClure, PhD, is assistant professor of psychiatry, and director of the Advanced Psychology Fellowship at Mount Sinai School of Medicine in New York City. Dr. McNamara McClure reports no affiliation with or financial interest in any organization that may pose a conflict of interest.
Activity Review Information
The activity content has been peer reviewed by Margaret McNamara McClure, PhD.
Review Date: May 14, 2010.
Acknowledgment of Commercial Support
This activity is supported by an educational grant from Lilly USA, LLC. For further information concerning Lilly grant funding visit www.lillygrantoffice.com.
To Receive Credit for this Activity
Read this Expert Panel Supplement, reflect on the information presented, and complete the CME posttest and evaluation on pages 14 and 15. To obtain credit, you should score 70% or better. Early submission of this posttest is encouraged. Please submit this posttest by July 1, 2012 to be eligible for credit.
Release date: July 31, 2010
Termination date: July 31, 2012
The estimated time to complete this activity is 2 hours.
CME Podcast Version
A related audio CME PsychCastTM will also be available online at: cmepsychcast.mblcommunications.com and via the “Science & Medicine” section of iTunes.
Below are selected resources for both physicians and patients of the clinical trials (both current and completed), national organizations, informational web sites, and support groups regarding the treatment of schizophrenia. This page is intended to be photocopied as a reference for the clinician and as a hand-out to patients.